Abstract: Two Y-linked short-tandem-repeat polymorphisms (DYS19 and DYS390) were analyzed by Genescan in an “insulated” population in the center of the Taklamakan desert of Xinjiang province. And 51 unrelated male individuals were also studied. The allelic distribution of DYS19 in this Keriyan population shows “M” shape. DYS19 ＊14 and DYS19 ＊16 are the most common allele, frequencies of which are 0.353 and 0.510, respectively. As DYS390 ＊21 owns the least repeat number and DYS390 ＊24 are the most common allele.This study suggeststhat the ancestor of Keriyan population is derived from two distinct origins.

Key words: Y-Chromosome; “Insulated” population; Short-tandem-repeat; Polymorphism