Abstract: To determine the genetic polymorphism of four X-STR loci among 167 unrelated individuals (57 female, 110 male) for Maonan groups from Guangxi Province, DXS7133, DXS8378, DXS6789 and DXS7423 were genotyped by multiplex PCR and Genscan. The numbers of alleles in the four X-STR loci were 4, 5, 9 and 3, respectively; the numbers of genotypes in the four loci were 5, 9, 18 and 5, respectively. The genotype frequencies in females were in accordance with Hardy-Weinberg equilibrium (P>0.05). The combined polymorphism information content (PIC) was 0.9611, power of discrimination (DP) was 0.9771 in males and 0.0.9980 in females, and the combined mean exclusion chance (MEC) was 0.0.9611 in the trio cases and 0.8821 in the duo cases. The 4 X-STR loci were highly polymorphic in Guangxi Maonan population and it is powerful for individual identification, paternity testing and population genetics. As well as the human population genetics and forensic science research offers Guangxi Maonan group X-STR loci of basic data, enrich the genetic database of the Chinese nation.

Key words: X-chromosome; Short tandem repeats; Genetic polymorphism; Genetic distance; Guangxi Maonan ethnic group