Reconstructing the genetic stemma of Sima Guang family

doi:10.16359/j.cnki.cn11-1963/q.2017.0081

Abstract

Abstract:

Genetic family trees, especially those of celebrities, have become the research focuses of genetic genealogy in recent years. Among them, the history of Sima Guang’s family tree has lasted for a thousand years with full records, which provides a good case for cross-disciplinary studies. In this study, eleven clans claiming to be descendants of Sima Guang were genotyped for 17 Y chromosomal short tandem repeats (STRs). The results indicated that five clans of them showed very close (the maximum number of mutation steps was four) relationships on their STR hyplotypes. Further tests of single nucleotide polymorphisms(SNPs) showed that they all belonged to a downstream haplogroup O1a1a1a1a1a-F492+,F656-. So, we can infer Sima Guang’s paternal lineage was most likely to be that haplogroup. Furthermore, a genealogical tree based on stemmata from these clans was constructed. Then, in order to verify the authenticity of the tree, we calculated the most recent common ancestor (TMRCA) of these clans hierarchically using BATWING method. And we found the time nodes recorded in the tree were in accordance with the TMRCA. This study offered a successful case of using paternal lineage to collate and reconstruct family pedigree. In addition, this investigation will facilitate studies on Sima Qian and the imperial house of the Western Jin Dynasty

Key words: Sima Guang, Genetic genealogy, Y chromosome, Paternal genetic lineage, SnaPshot

CLC Number:

Q987

DU Panxin, WEN Shaoqing, WANG Lingxiang, WEI Lanhai, MENG Hailiang, XIONG Jianxue, BAO Ruoyu, HAN Sheng, LI Hui. Reconstructing the genetic stemma of Sima Guang family[J]. Acta Anthropologica Sinica, 2019, 38(02): 304-316.

Figures/Tables 8

References 46

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SNP	物理位置(hg 19)	突变	PCR引物	延伸引物
F492	18615814	G->C	FOR TCTCCCAAGTTTGCTATCCCA	AAGAAAATGACCTTTGTT
F492	18615814	G->C	REV CACGGAATTTCAGCTTCTGATC	AAGAAAATGACCTTTGTT
F656	23757974	C->T	FOR GGGCAGGATGAACGGAGGCA	TTTTGTCTGTGGAAGATGGCC (反向)
F656	23757974	C->T	REV GGAGGACGCGGGAAACTGCT	TTTTGTCTGTGGAAGATGGCC (反向)

SNP	物理位置(hg 19)	突变	PCR引物	延伸引物
F492	18615814	G->C	FOR TCTCCCAAGTTTGCTATCCCA	AAGAAAATGACCTTTGTT
F492	18615814	G->C	REV CACGGAATTTCAGCTTCTGATC	AAGAAAATGACCTTTGTT
F656	23757974	C->T	FOR GGGCAGGATGAACGGAGGCA	TTTTGTCTGTGGAAGATGGCC (反向)
F656	23757974	C->T	REV GGAGGACGCGGGAAACTGCT	TTTTGTCTGTGGAAGATGGCC (反向)

Clan	EMR		lmMR		OMRB		OMRS
Clan	TMRCA	95% CI	TMRCA	95% CI	TMRCA	95% CI	TMRCA	95% CI
SX-WXC-XX	4371.3	569.2-31873.6	1160.7	159.5-7616.8	1147.6	157.3-7545.2	911.6	121.9-6086.5
SX-WXC	4405.4	353.1-48602.5	1145.7	87.6-12491.4	1120.5	85.9-12328.3	898.0	66.1-10179.8
SX-XX	1204.4	50.0-16042.0	328.3	12.6-4604.3	312.7	12.1-4392.6	247.3	9.3-3589.0
WXC-XX	4446.4	553.3-32870.1	1213.3	156.0-8263.8	1182.5	152.2-8083.7	948.9	119.2-6623.7
WXC	3833.7	210.6-53229.6	1007.8	48.2-15604.5	978.1	45.8-15397.8	774.5	34.8-12630.9
XX	--	--	--	--	--	---	--	--

Clan	EMR		lmMR		OMRB		OMRS
Clan	TMRCA	95% CI	TMRCA	95% CI	TMRCA	95% CI	TMRCA	95% CI
SX-WXC-XX	4371.3	569.2-31873.6	1160.7	159.5-7616.8	1147.6	157.3-7545.2	911.6	121.9-6086.5
SX-WXC	4405.4	353.1-48602.5	1145.7	87.6-12491.4	1120.5	85.9-12328.3	898.0	66.1-10179.8
SX-XX	1204.4	50.0-16042.0	328.3	12.6-4604.3	312.7	12.1-4392.6	247.3	9.3-3589.0
WXC-XX	4446.4	553.3-32870.1	1213.3	156.0-8263.8	1182.5	152.2-8083.7	948.9	119.2-6623.7
WXC	3833.7	210.6-53229.6	1007.8	48.2-15604.5	978.1	45.8-15397.8	774.5	34.8-12630.9
XX	--	--	--	--	--	---	--	--