我国瑶、汉、壮、苗、维五个民族补体成份B因子多态性的调查报告

人类学学报 ›› 1989, Vol. 8 ›› Issue (03): 269-273.

我国瑶、汉、壮、苗、维五个民族补体成份B因子多态性的调查报告

翦必希,赵修竹,程健华,洪涛,田廷武,江策,吴雄文,朱作金,张明安,尹经正,黄莲宝,郭炯

出版日期:1989-09-15 发布日期:1989-09-15

Genetic polymorphism of component Factor B (Bf) in Yao, Han, Zhuang, Miao and Uigur Nationalities in China

Jian Bixi, Zhao Xiuzhu, Cheng Jianhua, Hong Tao, Tian Yanwu, Wang Ce, Wu Xiongwen, Zhu Zuojin, Zhang Mingan, Yin Jingzheng, Huang Lianbao, Guo Jiong

Online:1989-09-15 Published:1989-09-15

摘要/Abstract

摘要： 用琼脂糖凝胶高压电泳及免疫固定技术对我国瑶、汉、壮、苗、维五个民族人群的补体B因子(Bf)的多态性进行了检测,结果显示,这五个民族的Bf基因频率均以s型最高,但参差不齐。从高到低的顺序是瑶0.9071,汉0.8727,壮0.8426,苗0.7667,维0.6622。BfF基因频率其次,但也高低不一,从高到低的顺序是维0.2680,苗0.2000,壮0.1343,汉0.1159,瑶0.0929。频率居第三位的是BfSO7,差别显著,维0.0586,苗0.0333,壮0.0232,汉0.0091,瑶0.0000。在罕见型方面,220例份汉族人中发现一例SO45杂合子,222例份维族中检出4例FO65及1例F1杂合子。本文结合我国其他民族及全球大量检测数据进行了一些对比讨论。

关键词: 补体;B因子;遗传多态性;人类遗传学

Abstract: The complement component factor B (Bf) polymorphism of Yao, Han, Zhuang, Miao and Uigur in China was investigated by means of high voltage agarose gel electrophoresis and sebsequent immunofixation. The results showed that the Bf*S gene frequencies were the highest in all five ethnic groups. These were Yao 0.9071, Han 0.8727, Zhuang 0.8426, Miao 0.7667, and Uigur 0.6622, respectively. The Bf*F was the second major gene in these ethnic groups: Uigur 0.2680, Miao 0.2000, Zhuang 0.1343, Han 0.1159 and Yao 0.0929, respectively. The BfSO7 was the less common gene: Uigur 0.0586, Miao 0.0333, Zhuang 0.0231, Han 0.0091, and Yao 0.0000, respectively. In addition, some rare phenotypes were found, such as SO 45 in Han and FO 65 and F1 in Uigur.

Key words: Properdin factor B; Genetic polymorphism; Human genetics

翦必希,赵修竹,程健华,洪涛,田廷武,江策,吴雄文,朱作金,张明安,尹经正,黄莲宝,郭炯. 我国瑶、汉、壮、苗、维五个民族补体成份B因子多态性的调查报告[J]. 人类学学报, 1989, 8(03): 269-273.

Jian Bixi, Zhao Xiuzhu, Cheng Jianhua, Hong Tao, Tian Yanwu, Wang Ce, Wu Xiongwen, Zhu Zuojin, Zhang Mingan, Yin Jingzheng, Huang Lianbao, Guo Jiong. Genetic polymorphism of component Factor B (Bf) in Yao, Han, Zhuang, Miao and Uigur Nationalities in China[J]. Acta Anthropologica Sinica, 1989, 8(03): 269-273.