汉族9个人群AcP_1、EsD及6-PGD的遗传多态性

人类学学报 ›› 1997, Vol. 16 ›› Issue (02): 159-166.

汉族9个人群AcP_1、EsD及6-PGD的遗传多态性

徐玖瑾,谭茜,杜若甫

出版日期:1997-06-15 发布日期:1997-06-15

Genetic polymorphism of AcP1 , EsD and 6-PGD in nine Han subpopulations of China

Xu Jiujin, Tan Qian, Du Ruofu

Online:1997-06-15 Published:1997-06-15

摘要/Abstract

摘要： 用淀粉凝胶电泳法对我国汉族9个人群的红细胞酸性磷酸酶(AcP1)、酯酶D(EsD)、及6-磷酸葡萄糖酸脱氢酶(6-PGD)的遗传多态性进行了研究。研究结果表明:兰州、呼和浩特、哈尔滨、西安、郑州、成都、贵阳、漳州、梅州等9市汉族人群的AcPB1基因频率依次为0.7929、0.8167、0.7938、0.8131、0.8088、0.8005、0.7896、0.7794和0.7675;EsD1基因频率依次为0.6473、0.6148、0.6443、0.6439、0.6475、0.6305、0.6287、0.5907和0.5825;6-PGOA基因频率依次为0.8881、0.9143、0.9330、0.9318、0.8756、0.9212、0.9188、0.9461和0.9375。EsD1基因频率在中国南、北方人群间有差异，北方人群的EsD1频率高于南方人群，随着北纬纬度由高向低，汉族人群EsD1频率也随着从北向南降低。在中国汉族人群中，EsD基因及6-PGD基因分化比较显著，而AcP基因分化则不显著。

关键词: 红细胞酸性磷酸酶;酯酶;6－磷酸葡萄糖酸脱氢酶;汉族;遗传多态性

Abstract: The genetic polymorphism of red cell acid phosphatase ( AcP) , Esterase D ( EsD) and 6- Phosphogluconate dehydrogenase ( 6- PGD) in nine Ha n subpopulations of China w as studied by starch gel electrophoresis. The results show ed that the gene frequencies o f AcPB1 in Han subpopalations from Lanzhou, Huhhot, Harbin, Xi 'a n, Zheng zhou, Cheng du, Guiyang , Zhang zhou and Meixian W ere 0. 7929, 0. 8167, 0. 7938, 0. 8131, 0. 8088, 0. 8005, 0. 7896, 0. 7794 and 0. 7675; EsD1 gene frequencies w ere o. 6473, 0. 6148, 0. 6443, 0. 6439, 0. 6475, 0. 6305, 0. 6287, 0. 5907 and 0. 5825; and 6- PGDA gene frequencies w ere 0. 8881, 0. 9143, 0. 9330, 0. 9318, 0. 8756, 0. 9212, 0. 9188, 0. 9461 and 0. 9375, respectively. The EsD1 gene frequencies in Southern subpopulations o f the Han ethnic group in China a re quite different from those o f the Northern ones, which are higher than those of the Southern subpopulations, and lower gradually along with the decrease of latitude. The divergence of EsD and 6- PGD genes among Han subpopulations is quite significant while that of AcP gene not.

Key words: AcP1 , 6- PGD, EsD, Genetic polymorphism, Han

徐玖瑾,谭茜,杜若甫. 汉族9个人群AcP_1、EsD及6-PGD的遗传多态性[J]. 人类学学报, 1997, 16(02): 159-166.

Xu Jiujin, Tan Qian, Du Ruofu. Genetic polymorphism of AcP1 , EsD and 6-PGD in nine Han subpopulations of China[J]. Acta Anthropologica Sinica, 1997, 16(02): 159-166.