应用Y染色体多态标记对汉族王姓亲缘关系的研究

人类学学报 ›› 2000, Vol. 19 ›› Issue (02): 132-137.

应用Y染色体多态标记对汉族王姓亲缘关系的研究

吴东颖,马素参,刘明,黄尚志,刘春芸

出版日期:2000-06-15 发布日期:2000-06-15

Application of Y-chromosome polymorphisms to studying the kinship of the males with family name wang from Han nationality

Wu Dongying, Ma Sucan, Liu Ming, Huang Shangzhi, Liu Chunyun

Online:2000-06-15 Published:2000-06-15

摘要/Abstract

摘要： Y染色体除拟常染色体区外 ,其它区域均缺乏重组 ,因而可保留其祖先历史上所发生的突变事件。作为研究父系遗传的工具 ,Y染色体多态具有独特的作用。中国传统上姓氏由父亲传给子女 ,遵循父系传递。本实验应用 Y染色体的 4个微卫星标记 (即 DYS1 9、DYS390、DYS391和 YCA2 ) ,对 50例北京汉族王姓男性 DNA样本进行了多态性分析 ,并与本实验室对 50例汉族男性随机样本应用前 3个位点检测的结果相比较 ,结果表明 :北京汉族王姓男性携带的 Y染色体单体型与对照无差异。王姓有复杂的多起源可能可以解释这一结果。

关键词: Y染色体;姓氏;DNA多态;微卫星标记

Abstract: Y chromosome does not recombine at meiosis except its pesudoautosomal region, so it keeps a record of its ancestor 's mutations in the history. As a marker for the study of paternal heredity, Y chromosome polymorphisms play a special role. Using four Y specific microsatellite markers, we carried out a DN A polymorphism analysis of fifty unrelated males randomly picked up from the Han nationality with the family name Wang . There were no difference between the results above and the result of another study, which used the same 3 markers ( DYS19, DYS390, DYS391) to investigate 50 males with different family names randomly chosen from Han nationality. It is concluded that there are no significant difference between haplo types of the males with family name Wang in Beijing and those of random sample of males from Han nationality, which can be explained by the complex origins of family name Wang.

Key words: Y chromosome, DNA polymorphism, Microsatellite, Family name

吴东颖,马素参,刘明,黄尚志,刘春芸. 应用Y染色体多态标记对汉族王姓亲缘关系的研究[J]. 人类学学报, 2000, 19(02): 132-137.

Wu Dongying, Ma Sucan, Liu Ming, Huang Shangzhi, Liu Chunyun. Application of Y-chromosome polymorphisms to studying the kinship of the males with family name wang from Han nationality[J]. Acta Anthropologica Sinica, 2000, 19(02): 132-137.