MYS2多态位点在中国26个人群中分布的研究

人类学学报 ›› 2003, Vol. 22 ›› Issue (01): 63-68.

MYS2多态位点在中国26个人群中分布的研究

薛雅丽,包维东,傅松滨,Tatiana Zerjal,朱苏玲,徐玖瑾,杜若甫,张贵寅,李璞,Chris Tyler-Smith

出版日期:2003-03-15 发布日期:2003-03-15

The distribution of MYS2 polymorphism in 26 Chinese populations

XUE Ya-li; ; BAO Wei-dong; FU Song-bin; Tatiana Zerjal; ZHU Su-ling; XU Jiu-jin; DU Ruo-fu; ZHANG Guiyin; LI Pu; Chris Tyler-Smith

Online:2003-03-15 Published:2003-03-15

摘要/Abstract

摘要： 对中国26个人群中Y染色体小卫星位点MYS2的分布进行了研究，结果显示：MYS2*4是常见的等位基因类型，MYS2*3在中国不同人群中分布差异很大（0—324%）；并对该位点在不同人群中分布的频率进行了AMOVA分析，结果为：不分组、南方人群和北方人群的遗传学差异分别为7.76%、8.11%和1.42%。南北方人群间、东北和西北人群间的差异分别为4.34%和1.57%。结论：MYS2是研究中国人群遗传结构有价值的多态位点，中国不同人群之间存在一定的遗传学差异，中国南方人群间的遗传学差异较大，再次证实了中国人群的南北差异。

关键词: Y染色体；MYS2；AMOVA；中国人群

Abstract: The distribution of MYS2 polymorphism in 26 Chinese populations was analyzed by PCR. And the variations of intra- and between populations were calculated using AMOVA by Arlequin Package. MYS2＊4 was the common allele while the incidence of MYS2＊3 was much different in these pop- ulations. By AMOVA, 7. 76 %、8. 11 % and 1. 42 %of total variation were found among all 26, 10 Southern and 16 Northern Chinese populations respectively. And 4. 34 %of total variation was found between the Southern and Northern groups while 1. 57 %was found between northeast and northwest groups. The results showed that MYS2 polymorphism is very useful in analyzing the genetic structure of Chinese population. Some difference in genetic structure was seen among the different populations and a geographical distinction between South and North was confirmed. The distinction between Western and Eastern populations in the Northern China was also suggested.

Key words: Y chromosome; MYS2; AMOVA; Chinese populations

薛雅丽,包维东,傅松滨,Tatiana Zerjal,朱苏玲,徐玖瑾,杜若甫,张贵寅,李璞,Chris Tyler-Smith. MYS2多态位点在中国26个人群中分布的研究[J]. 人类学学报, 2003, 22(01): 63-68.

XUE Ya-li; ; BAO Wei-dong; FU Song-bin; Tatiana Zerjal; ZHU Su-ling; XU Jiu-jin; DU Ruo-fu; ZHANG Guiyin; LI Pu; Chris Tyler-Smith. The distribution of MYS2 polymorphism in 26 Chinese populations[J]. Acta Anthropologica Sinica, 2003, 22(01): 63-68.