山东汉族人群中13个快速突变(RM)Y-STR基因座的多态性

doi:10.16359/j.cnki.cn11-1963/q.2017.0073

人类学学报 ›› 2019, Vol. 38 ›› Issue (02): 292-303.doi: 10.16359/j.cnki.cn11-1963/q.2017.0073

山东汉族人群中13个快速突变(RM)Y-STR基因座的多态性

陈玉玲¹^,²(), 李敏², 赵珍敏², 李亚男², 包云², 盛翔², 朱如心², 王亚丽², 马兴元¹^,^*()

1.华东理工大学生物工程学院生物反应器工程国家重点实验室,上海 200237
2.司法部司法鉴定科学技术研究所,上海市法医学重点实验室,上海市司法鉴定专业技术服务平台,上海 200063

收稿日期:2017-02-15 修回日期:2017-05-21 出版日期:2019-05-15 发布日期:2020-09-10
通讯作者: 马兴元
作者简介:陈玉玲（1992-）,女,华东理工大学生物工程学院生物反应器工程国家重点实验室及司法部司法鉴定科学技术研究所研究生,主要从事法医遗传学研究,E-mail: 616210168@qq.com
基金资助:
“十三五”国家重点研发项目资助(2016YFC0800703);国家自然科学基金(81601651);国家自然科学基金(81625013);中央级公益性科研院所项目(GY2016G-4);上海市“科技创新行动计划”项目(16dz1205500)

Genetic Polymorphism of 13 RM Y-STR Loci in Shandong Population

CHEN Yuling¹^,²(), LI Min², ZHAO Zhenmin², Li Yanan², BAO Yun², ZHU Ruxin², SHENG Xiang², WANG Yali², MA Xingyuan¹^,^*()

1. School of Biotechnology and State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237
2. Shanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Science, Ministry of Justice, Shanghai 200063

Received:2017-02-15 Revised:2017-05-21 Online:2019-05-15 Published:2020-09-10
Contact: MA Xingyuan

摘要/Abstract

摘要：

本研究旨在调查13个快速突变Y染色体STR基因座 (RM Y-STR) 在山东汉族人群中的等位基因频率以及遗传多态性。采集154个山东无关男性个体FTA卡血液样本。采用13 个RM Y-STR PCR复合扩增体系进行扩增以及AB 3130 XL遗传分析仪进行Y-STR分型,并对分型结果进行相关统计,检测13个RM Y-STR位点遗传多态性分布。本研究在13个基因座上共检测出331个等位基因,基因型多态性 (GD) 分布在0.7643 (DYS576)~0.9946 (DYF399S1abc) 之间。通过13个RM Y-STR基因座在154名山东汉族男性无关个体中共检测出154种单倍型,无共享单倍型现象出现。总的单倍型多样性 (HD值) 为1,识别能力 (DC值) 为1。故13个RM Y-STR基因座组成的分型系统在山东汉族人群中表现出很强的个体识别能力,具有重要的法医学应用价值。

关键词: 快速突变, 遗传多态性, 单倍型, 山东, Y染色体

Abstract:

To verify the allele frequency and the haplotype diversity of the 13 rapidly mutating (RM) Y-STRs in Shandong province, Chinese Han population, we collected 154 unrelated male blood samples on FTA cards, and amplified the 13 RM Y-STRs with multiple PCR and tested the genotype using 3130XL (ABI) Genetic Analyzer. Among 13 RM Y-STRs, we observed a total of 331 alleles, and the values of gene diversity for each STR ranged from 0.7643 (DYS576) ~ 0.9946 (DYF399S1abc). Altogether 154 different haplotypes were identified from 154 unrelated male individuals and the haplotype diversity reached 1. We make a Conclusion that 13 RM Y-STRs show strong discrimination power and great application value for forensic in Shandong Han population.

Key words: Rapidly mutating, Genetic polymorphic, Haplotype, Shandong, Y-chromosome

中图分类号:

Q987

陈玉玲, 李敏, 赵珍敏, 李亚男, 包云, 盛翔, 朱如心, 王亚丽, 马兴元. 山东汉族人群中13个快速突变(RM)Y-STR基因座的多态性[J]. 人类学学报, 2019, 38(02): 292-303.

CHEN Yuling, LI Min, ZHAO Zhenmin, Li Yanan, BAO Yun, ZHU Ruxin, SHENG Xiang, WANG Yali, MA Xingyuan. Genetic Polymorphism of 13 RM Y-STR Loci in Shandong Population[J]. Acta Anthropologica Sinica, 2019, 38(02): 292-303.

图/表 5

参考文献 23

[1]	Jobling MA, Tyler-Smith C. Fathers and sons: The Y chromosome and human evolution[J]. Trends Genet, 1995,11(11):449-456 doi: 10.1016/s0168-9525(00)89144-1 URL pmid: 8578602
[2]	Underhill PA, Kivisild T. Use of y chromosome and mitochondrial DNA population structure in tracing human migrations[J]. Annu Rev Genet, 2007,41:539-564 doi: 10.1146/annurev.genet.41.110306.130407 URL pmid: 18076332
[3]	Jobling MA, Pandya A, Tyler-Smith C. The Y chromosome in forensic analysis and paternity testing[J]. Int J Legal Med, 1997,110(3):118-124 doi: 10.1007/s004140050050 URL pmid: 9228562
[4]	De Knijff P, Kayser M, Caglia A, et al. Chromosome Y microsatellites: population genetic and evolutionary aspects[J]. Int J Legal Med, 1997,110(3):134-149 doi: 10.1007/s004140050052 URL pmid: 9228564
[5]	Ballantyne KN, Keerl V, Wollstein A, et al. A new future of forensic Y-chromosome analysis: Rapidly mutating Y-STRs for differentiating male relatives and paternal lineages[J]. Forensic Science International Genetics, 2011,6(2):208-218 doi: 10.1016/j.fsigen.2011.04.017 URL pmid: 21612995
[6]	Kayser M, Caglia A, Corach D, et al. Evaluation of Y-chromosomal STRs: A multicenter study[J]. Int J Legal Med, 1997, 110(3): 125-133, 141-149 doi: 10.1007/s004140050051 URL pmid: 9228563
[7]	Goedbloed M, Vermeulen M, Fang RN, et al. Comprehensive mutation analysis of 17 Y-chromosomal short tandem repeat polymorphisms included in the AmpFlSTR® Yfiler® PCR amplification kit[J]. International Journal of Legal Medicine, 2009,123(6):471-482 doi: 10.1007/s00414-009-0342-y URL
[8]	Kayser M, Roewer L, Hedman M, et al. Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs[J]. Am J Hum Genet, 2000,66(5):1580-1588 doi: 10.1086/302905 URL pmid: 10762544
[9]	Ballantyne KN, Goedbloed M, Fang R, et al. Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases, and forensic implications[J]. Am J Hum Genet, 2010,87(3):341-353 doi: 10.1016/j.ajhg.2010.08.006 URL
[10]	Ballantyne KN, Ralf A, Aboukhalid R, et al. Toward male individualization with rapidly mutating y-chromosomal short tandem repeats[J]. Hum Mutat, 2014,35(8):1021-1032 doi: 10.1002/humu.22599 URL
[11]	Parson W, Niederstätter H, Brandstätter A, et al. Improved specificity of Y-STR typing in DNA mixture samples[J]. International Journal of Legal Medicine, 2003,117(2):109-114 doi: 10.1007/s00414-002-0327-6 URL pmid: 12772701
[12]	Prinz M, Boll K, Baum H, et al. Multiplexing of Y chromosome specific STRs and performance for mixed samples[J]. Forensic Science International, 1997,85(3):209-18 doi: 10.1016/s0379-0738(96)02096-8 URL pmid: 9149405
[13]	Coble MD, Hill CR, Butler JM. Haplotype data for 23 Y-chromosome markers in four U.S. population groups[J]. Forensic Sci Int Genet, 2013,7(3):e66-e68 doi: 10.1016/j.fsigen.2013.03.006 URL pmid: 23578807
[14]	Alghafri R, Alhammadi S, Amiri K. A comparison between Yfiler® and RM Y-STRs in United Arab Emirates population[J]. Forensic Science International: Genetics Supplement Series, 2015,5:e650-e652 doi: 10.1016/j.fsigss.2015.10.012 URL
[15]	Rossi E, Rolf B, Schurenkamp M, et al. Y-chromosome STR haplotypes in an Italian population sample[J]. Int J Legal Med, 1998,112(1):78-81 doi: 10.1007/s004140050206 URL pmid: 9932751
[16]	王新杰, 许欣, 黄磊, 等. 山东汉族人群63个Y-STR基因座突变观察及法医学应用[J].刑事技术, 2016(5):424-428
[17]	Zhang W, Xiao C, Wei T, et al. Haplotype diversity of 13 RM Y-STRs in Chinese Han population and an update on the allele designation of DYF403S1[J]. Forensic Sci Int Genet, 2016,23:e1-e9 doi: 10.1016/j.fsigen.2016.04.013 URL pmid: 27217255
[18]	贾东涛, 徐中华, 王守宇. 新疆维吾尔族群体22个Y-STR基因座的多态性分析[J].法医学杂志, 2016(03):224-226
[19]	杨洪毅, 徐朝阳, 宋丽君, 等. 河南汉族14个Y-STR基因位点单倍型的遗传多态性[J]. 郑州大学学报(医学版), 2012(02):223-225
[20]	孙凯臻, 彭珊, 刘超, 等. 广东汉族群体24个Y-STR基因座的多态性及突变率[J].中国法医学杂志, 2014(06):514-518
[21]	马立宇, 胡利平, 聂爱婷, 等. 南白族人群13个快速突变(RM)Y-STR基因座多态性研究[J].昆明医科大学学报, 2015(07):170-177
[22]	Han Y, Li L, Liu X, et al. Genetic analysis of 17 Y-STR loci in Han and Korean populations from Jilin Province, Northeast China[J]. Forensic Science International Genetics, 2016,22:8-10 URL pmid: 26799315
[23]	Li L, Yu G, Li S, et al. Genetic analysis of 17 Y-STR loci from 1019 individuals of six Han populations in East China[J]. Forensic Science International Genetics, 2016,20:101 doi: 10.1016/j.fsigen.2015.10.007 URL pmid: 26529186

DYS626		DYF403S1b1		DYS404S1ab		DYF387S1ab		DYF403S1a
等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率
26	1.30%	15.2	2.60%	12-13 13	5.20%	34	0.60%	32-34	0.60%
27	2.60%	16.2	9.70%	12-14	0.60%	34.2-38	0.60%	34-36	0.60%
28	19.50%	17.2	18.20%	12-15	1.30%	34-37	2.60%	34-39	1.30%
29	22.10%	18.2	20.80%	13	18.20%	34-38	1.30%	35.2-42	0.60%
30	16.20%	19.2	18.20%	13-14	20.10%	34-39	3.20%	35-37	0.60%
31	19.50%	20.2	12.30%	13-15	5.80%	34-41	0.60%	35-38	1.90%
32	7.10%	21.2	11.00%	13-16	4.50%	35	1.30%	35-39	1.30%
33	5.80%	22.2	4.50%	14	9.10%	35-37	1.90%	35-41	0.60%
34	5.20%	23.2	1.90%	14-15	7.80%	35-38	14.30%	35-42	0.60%
35	0.60%	24.2	0.60%	14-15-16	0.60%	35-39	7.10%	36	1.30%
DYS449		DYF403S1b2		14-16	3.90%	35-40	0.60%	36-37	1.90%
等位基因	频率	等位基因	频率	14-17	1.90%	36	5.20%	36-38	3.90%
26	1.90%	51.2	2.60%	14-18	0.60%	36-37	6.50%	36-40	1.30%
27	4.50%	52.2	3.20%	15	10.40%	36-38	9.10%	36-42	0.60%
28	7.80%	53.2	2.60%	15-16	5.20%	36-39	5.20%	36-43	0.60%
29	9.70%	54.2	1.30%	15-16-17	0.60%	36-40	3.20%	36-45	0.60%
30	10.40%	55.2	3.90%	16	1.30%	36-41	1.30%	37	1.30%
31	16.20%	56.2	7.80%	16	1.30%	36-42	0.60%	37-38	7.10%
32	13.00%	57.2	9.10%	16-17	1.90%	37	2.60%	37-39	1.90%
33	13.60%	58.2	14.90%	17	0.60%	37-38	8.40%	37-40	2.60%
34	13.60%	59.2	14.30%	DYS526a		37-39	1.90%	37-41	1.30%
35	6.50%	60.2	15.60%	等位基因	频率	37-40	1.30%	37-42	1.90%
36	1.30%	61.2	13.60%	12	11.00%	37-41	0.60%	37-43	2.60%
37	0.60%	62.2	5.80%	13	20.10%	38	5.20%	38	4.50%
38	0.60%	63.2	2.60%	14	29.20%	38-39	1.30%	38.2-41	0.60%
DYS627		64.2	2.60%	15	28.60%	38-40	3.90%	38-39	5.20%
等位基因	频率	DYS612		16	10.40%	38-41	0.60%	38-40	5.20%
16	1.30%	等位基因	频率	17	0.60%	38-42	0.60%	38-41	3.20%
17	3.20%	31	1.30%	DYS526b		39	1.90%	38-42	1.30%
18	15.60%	32	4.50%	等位基因	频率	39-40	3.20%	39	1.90%
19	13.60%	33	4.50%	33	0.60%	40	1.90%	39-40	8.40%
20	20.80%	34	9.70%	34	5.20%	40-41	0.60%	39-41	5.20%
21	16.20%	35	9.70%	35	11.00%	DYS518		39-42	1.90%
21.2	0.60%	36	18.80%	36	15.60%	等位基因	频率	40	5.80%
22	16.90%	37	18.20%	37	33.80%	33	1.30%	40-41	4.50%
23	6.50%	38	12.30%	38	21.40%	34	3.20%	40-43	1.90%
24	4.50%	39	17.50%	39	9.70%	35	12.30%	40-44	0.60%
25	0.60%	40	3.20%	40	2.60%	36	24.70%	41	1.30%
DYS576		DYS547		DYS570		36.2	0.60%	41-42	0.60%
等位基因	频率	等位基因	频率	等位基因	频率	37	16.90%	41-43	3.20%
10	0.60%	42	3.20%	14	2.60%	37.2	0.60%	41-44	0.60%
14	0.60%	43	2.60%	15	4.50%	38	14.90%	41-46	0.60%
15	1.30%	44	3.20%	16	20.80%	39	14.30%	42	1.30%
16	7.80%	45	5.20%	17	21.40%	40	3.90%	42-43	1.30%
17	15.60%	46	7.10%	18	23.40%	41	4.50%	42-44	1.30%
18	39.60%	47	16.90%	19	20.80%	42	0.60%	42-46	0.60%
19	20.10%	48	26.00%	20	5.20%	43	0.60%	43-45	0.60%
20	11.00%	49	14.30%	21	1.30%	44	0.60%
21	2.60%	50	13.00%			46	0.60%
22	0.60%	51	3.90%
		52	4.50%
DYF399S1abc
等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率
16-22-23	0.60%	20-23.1-24.1	0.60%	21-22-26.1	1.30%	21-26-27.1	0.60%	23.1-24-25	0.60%
16-25-27.1	0.60%	20-23.1-25	2.60%	21-23.1	1.30%	21-27.1	0.60%	23.1-24-26.1	0.60%
17.1-19-25	0.60%	20-23-24.1	1.30%	21-23.1-24	0.60%	22.1	0.60%	23-23.1	0.60%
18-23.1-25	0.60%	20-23-25.1	0.60%	21-23.1-25	1.30%	22.1-24	0.60%	23-24.1	1.30%
18-24-25.1	0.60%	20-23-26.1	0.60%	21-23-23.1	2.60%	22.1-25-26	0.60%	23-24.1-25	0.60%
19.1-21-27	0.60%	20-24	0.60%	21-23-24.1	1.30%	22-22.1	0.60%	23-24-24.1	1.30%
19.1-21-28	0.60%	20-24.1-25	0.60%	21-23-24-24.1	0.60%	22-22.1-23	0.60%	23-24-29.1	0.60%
19.1-21-28.2	0.60%	20-24-24.1	1.90%	21-23-25.1	0.60%	22-23	0.60%	24.1	0.60%
19.1-21-29	0.60%	20-24-25.1	0.60%	21-23-26.1	0.60%	22-23.1	1.30%	24.1-26	1.30%
19-20-24.1	0.60%	20-24-26.1	1.30%	21-23-27.1	0.60%	22-23.1-24	1.90%	24.1-26.1	0.60%
19-21.1-23	0.60%	20-24-27.1	1.30%	21-24.1-25	1.30%	22-23-25.1	0.60%	24-24.1-25	0.60%
19-21-23.1	1.30%	20-25.1	0.60%	21-24.1-26	1.30%	22-23-28	0.60%	24-25-26.1	0.60%
19-22.1-23	0.60%	20-25.1-26	0.60%	21-24-24.1	1.30%	22-24.1	0.60%	24-27.1	1.30%
19-23-26.1	0.60%	20-27.1	0.60%	21-24-25.1	2.60%	22-24.1-25	1.30%	25.1-27.1	0.60%
19-24-24.1	0.60%	21	1.30%	21-24-26.1	0.60%	22-24-24.1	0.60%	26.1	3.20%
19-26-26.1	0.60%	21.1	0.60%	21-24-27.1	1.30%	22-24-25.1	2.60%	28.1	0.60%
20.1-22-23	0.60%	21.1-22-24	0.60%	21-25.1-26	0.60%	22-24-27.1	1.30%	30.1	0.60%
20-22.1-25	1.30%	21.1-23-25	0.60%	21-25-25.1	1.90%	22-24-27.1	0.60%	31.1	0.60%
20-22-24.1	0.60%	21-21.1-22-23-23.1	0.60%	21-25-27.1	1.30%	22-26.1-27	0.60%
20-22-28.1	0.60%	21-22.1-23	0.60%	21-25-28.1	0.60%	22-27-27.1	0.60%
20-22-29.1	0.60%	21-22-22.1	1.30%	21-26.1-28	0.60%	23	0.60%
20-23.1-24	1.90%	21-22-23.1	0.60%	21-26-26.1	0.60%	23.1-24.1	1.30%

DYS626		DYF403S1b1		DYS404S1ab		DYF387S1ab		DYF403S1a
等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率
26	1.30%	15.2	2.60%	12-13 13	5.20%	34	0.60%	32-34	0.60%
27	2.60%	16.2	9.70%	12-14	0.60%	34.2-38	0.60%	34-36	0.60%
28	19.50%	17.2	18.20%	12-15	1.30%	34-37	2.60%	34-39	1.30%
29	22.10%	18.2	20.80%	13	18.20%	34-38	1.30%	35.2-42	0.60%
30	16.20%	19.2	18.20%	13-14	20.10%	34-39	3.20%	35-37	0.60%
31	19.50%	20.2	12.30%	13-15	5.80%	34-41	0.60%	35-38	1.90%
32	7.10%	21.2	11.00%	13-16	4.50%	35	1.30%	35-39	1.30%
33	5.80%	22.2	4.50%	14	9.10%	35-37	1.90%	35-41	0.60%
34	5.20%	23.2	1.90%	14-15	7.80%	35-38	14.30%	35-42	0.60%
35	0.60%	24.2	0.60%	14-15-16	0.60%	35-39	7.10%	36	1.30%
DYS449		DYF403S1b2		14-16	3.90%	35-40	0.60%	36-37	1.90%
等位基因	频率	等位基因	频率	14-17	1.90%	36	5.20%	36-38	3.90%
26	1.90%	51.2	2.60%	14-18	0.60%	36-37	6.50%	36-40	1.30%
27	4.50%	52.2	3.20%	15	10.40%	36-38	9.10%	36-42	0.60%
28	7.80%	53.2	2.60%	15-16	5.20%	36-39	5.20%	36-43	0.60%
29	9.70%	54.2	1.30%	15-16-17	0.60%	36-40	3.20%	36-45	0.60%
30	10.40%	55.2	3.90%	16	1.30%	36-41	1.30%	37	1.30%
31	16.20%	56.2	7.80%	16	1.30%	36-42	0.60%	37-38	7.10%
32	13.00%	57.2	9.10%	16-17	1.90%	37	2.60%	37-39	1.90%
33	13.60%	58.2	14.90%	17	0.60%	37-38	8.40%	37-40	2.60%
34	13.60%	59.2	14.30%	DYS526a		37-39	1.90%	37-41	1.30%
35	6.50%	60.2	15.60%	等位基因	频率	37-40	1.30%	37-42	1.90%
36	1.30%	61.2	13.60%	12	11.00%	37-41	0.60%	37-43	2.60%
37	0.60%	62.2	5.80%	13	20.10%	38	5.20%	38	4.50%
38	0.60%	63.2	2.60%	14	29.20%	38-39	1.30%	38.2-41	0.60%
DYS627		64.2	2.60%	15	28.60%	38-40	3.90%	38-39	5.20%
等位基因	频率	DYS612		16	10.40%	38-41	0.60%	38-40	5.20%
16	1.30%	等位基因	频率	17	0.60%	38-42	0.60%	38-41	3.20%
17	3.20%	31	1.30%	DYS526b		39	1.90%	38-42	1.30%
18	15.60%	32	4.50%	等位基因	频率	39-40	3.20%	39	1.90%
19	13.60%	33	4.50%	33	0.60%	40	1.90%	39-40	8.40%
20	20.80%	34	9.70%	34	5.20%	40-41	0.60%	39-41	5.20%
21	16.20%	35	9.70%	35	11.00%	DYS518		39-42	1.90%
21.2	0.60%	36	18.80%	36	15.60%	等位基因	频率	40	5.80%
22	16.90%	37	18.20%	37	33.80%	33	1.30%	40-41	4.50%
23	6.50%	38	12.30%	38	21.40%	34	3.20%	40-43	1.90%
24	4.50%	39	17.50%	39	9.70%	35	12.30%	40-44	0.60%
25	0.60%	40	3.20%	40	2.60%	36	24.70%	41	1.30%
DYS576		DYS547		DYS570		36.2	0.60%	41-42	0.60%
等位基因	频率	等位基因	频率	等位基因	频率	37	16.90%	41-43	3.20%
10	0.60%	42	3.20%	14	2.60%	37.2	0.60%	41-44	0.60%
14	0.60%	43	2.60%	15	4.50%	38	14.90%	41-46	0.60%
15	1.30%	44	3.20%	16	20.80%	39	14.30%	42	1.30%
16	7.80%	45	5.20%	17	21.40%	40	3.90%	42-43	1.30%
17	15.60%	46	7.10%	18	23.40%	41	4.50%	42-44	1.30%
18	39.60%	47	16.90%	19	20.80%	42	0.60%	42-46	0.60%
19	20.10%	48	26.00%	20	5.20%	43	0.60%	43-45	0.60%
20	11.00%	49	14.30%	21	1.30%	44	0.60%
21	2.60%	50	13.00%			46	0.60%
22	0.60%	51	3.90%
		52	4.50%
DYF399S1abc
等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率	等位基因	频率
16-22-23	0.60%	20-23.1-24.1	0.60%	21-22-26.1	1.30%	21-26-27.1	0.60%	23.1-24-25	0.60%
16-25-27.1	0.60%	20-23.1-25	2.60%	21-23.1	1.30%	21-27.1	0.60%	23.1-24-26.1	0.60%
17.1-19-25	0.60%	20-23-24.1	1.30%	21-23.1-24	0.60%	22.1	0.60%	23-23.1	0.60%
18-23.1-25	0.60%	20-23-25.1	0.60%	21-23.1-25	1.30%	22.1-24	0.60%	23-24.1	1.30%
18-24-25.1	0.60%	20-23-26.1	0.60%	21-23-23.1	2.60%	22.1-25-26	0.60%	23-24.1-25	0.60%
19.1-21-27	0.60%	20-24	0.60%	21-23-24.1	1.30%	22-22.1	0.60%	23-24-24.1	1.30%
19.1-21-28	0.60%	20-24.1-25	0.60%	21-23-24-24.1	0.60%	22-22.1-23	0.60%	23-24-29.1	0.60%
19.1-21-28.2	0.60%	20-24-24.1	1.90%	21-23-25.1	0.60%	22-23	0.60%	24.1	0.60%
19.1-21-29	0.60%	20-24-25.1	0.60%	21-23-26.1	0.60%	22-23.1	1.30%	24.1-26	1.30%
19-20-24.1	0.60%	20-24-26.1	1.30%	21-23-27.1	0.60%	22-23.1-24	1.90%	24.1-26.1	0.60%
19-21.1-23	0.60%	20-24-27.1	1.30%	21-24.1-25	1.30%	22-23-25.1	0.60%	24-24.1-25	0.60%
19-21-23.1	1.30%	20-25.1	0.60%	21-24.1-26	1.30%	22-23-28	0.60%	24-25-26.1	0.60%
19-22.1-23	0.60%	20-25.1-26	0.60%	21-24-24.1	1.30%	22-24.1	0.60%	24-27.1	1.30%
19-23-26.1	0.60%	20-27.1	0.60%	21-24-25.1	2.60%	22-24.1-25	1.30%	25.1-27.1	0.60%
19-24-24.1	0.60%	21	1.30%	21-24-26.1	0.60%	22-24-24.1	0.60%	26.1	3.20%
19-26-26.1	0.60%	21.1	0.60%	21-24-27.1	1.30%	22-24-25.1	2.60%	28.1	0.60%
20.1-22-23	0.60%	21.1-22-24	0.60%	21-25.1-26	0.60%	22-24-27.1	1.30%	30.1	0.60%
20-22.1-25	1.30%	21.1-23-25	0.60%	21-25-25.1	1.90%	22-24-27.1	0.60%	31.1	0.60%
20-22-24.1	0.60%	21-21.1-22-23-23.1	0.60%	21-25-27.1	1.30%	22-26.1-27	0.60%
20-22-28.1	0.60%	21-22.1-23	0.60%	21-25-28.1	0.60%	22-27-27.1	0.60%
20-22-29.1	0.60%	21-22-22.1	1.30%	21-26.1-28	0.60%	23	0.60%
20-23.1-24	1.90%	21-22-23.1	0.60%	21-26-26.1	0.60%	23.1-24.1	1.30%

等位基因	D_g值	标准DNA9948基因分型	观察到等位基因范围
DYS526a	0.7746	14	12-17
DYS626	0.8423	28	26-35
DYS526b	0.7959	36	33-40
DYS627	0.8571	22	16-25
DYF403S1b1	0.8563	20.2	15.2-24.2
DYS612	0.8673	37	31-40
DYF403S1b2	0.8972	55.2	51.2-64.2
DYS576	0.7643	16	10-22
DYS570	0.8126	18	14-21
DYS547	0.8580	48	42-52
DYS518	0.8532	38	33-46
DYS449	0.8925	30	26-38
DYF404S1ab	0.8934	12-14	12-17
DYF399S1abc	0.9946	21-22-25.1	16-31.1
DYF387S1ab	0.9444	35-38	34-41
DYF403S1a	0.9688	35-40	32-45

等位基因	D_g值	标准DNA9948基因分型	观察到等位基因范围
DYS526a	0.7746	14	12-17
DYS626	0.8423	28	26-35
DYS526b	0.7959	36	33-40
DYS627	0.8571	22	16-25
DYF403S1b1	0.8563	20.2	15.2-24.2
DYS612	0.8673	37	31-40
DYF403S1b2	0.8972	55.2	51.2-64.2
DYS576	0.7643	16	10-22
DYS570	0.8126	18	14-21
DYS547	0.8580	48	42-52
DYS518	0.8532	38	33-46
DYS449	0.8925	30	26-38
DYF404S1ab	0.8934	12-14	12-17
DYF399S1abc	0.9946	21-22-25.1	16-31.1
DYF387S1ab	0.9444	35-38	34-41
DYF403S1a	0.9688	35-40	32-45

山东汉族人群中13个快速突变(RM)Y-STR基因座的多态性

Genetic Polymorphism of 13 RM Y-STR Loci in Shandong Population

在线阅读

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 5

参考文献 23

相关文章 15

编辑推荐

Metrics

本文评价

[1]	张金科, 董薇, 唐光峰, 黄晓亮, 杨振, 王晓军, 张杰, 赵英健, 朱奕卿, 江丽. 山东汉、回族男性人群父系遗传结构研究[J]. 人类学学报, 2022, 41(01): 65-72.
[2]	张晓雯, 郭俊峰, 王子孟, 郝导华, 赵永生, 朱超, 陈雪香, 曾雯. 山东古代人群头骨上蛛网膜颗粒压迹的观察与探讨[J]. 人类学学报, 2019, 38(02): 245-253.
[3]	杜盼新, 文少卿, 王凌翔, 韦兰海, 蒙海亮, 熊建雪, 包若瑜, 韩昇, 李辉. 重构司马光家族基因家谱[J]. 人类学学报, 2019, 38(02): 304-316.
[4]	陈福友;李罡;李玉;李锋;张双权;仪明洁. 山东日照黄泥梁旧石器时代遗址发掘简报[J]. 人类学学报, 2018, 37(04): 542-552.
[5]	李罡;任雅鹏;苏建军;马勇;徐西存. 山东省蒙阴县园艺场旧石器地点调查简报[J]. 人类学学报, 2018, 37(01): 88-95.
[6]	刘树虎;伊力哈木·乃扎木;热比亚木·巴克;布帕提玛穆·阿布都克热穆;多力坤·买买提玉素甫. 应用Y染色体SNP对新疆三个隔离人群遗传多样性的研究[J]. 人类学学报, 2018, 37(01): 146-156.
[7]	林壹;顾万发;汪松枝;何嘉宁;刘拓;陈宥成;赵潮;王幼平. 河南登封方家沟遗址发掘简报[J]. 人类学学报, 2017, 36(01): 17-25.
[8]	文少卿;王传超;敖雪;韦兰海;佟欣竹;王凌翔;王占峰;韩昇;李辉. 古DNA证据支持曹操的父系遗传类型属于单倍群O2[J]. 人类学学报, 2016, 35(04): 617-625.
[9]	葛威. 关于曹姓家族分子人类学研究的几个问题[J]. 人类学学报, 2016, 35(04): 626-632.
[10]	侯伟光;王传超;蒋世洪;刘海东;李辉. 曲阜地区孔姓人群17个Y-STR基因座遗传多态性分析[J]. 人类学学报, 2016, 35(01): 125-131.
[11]	周丽宁;龚继春;伦军;邓琼英;覃耀春. 广西毛南族DXS7133、DXS8378、DXS6789和DXS7423基因座遗传多态性[J]. 人类学学报, 2015, 34(03): 397-403.
[12]	陈福友;李罡;李玉;李锋. 山东日照黄泥梁遗址2012年调查与试掘[J]. 人类学学报, 2015, 34(01): 21-27.
[13]	王幼平;汪松枝. MIS3阶段嵩山东麓旧石器发现与问题[J]. 人类学学报, 2014, 33(03): 304-314.
[14]	贺永锋;陈利萍;赵杰;宋振. 陕西渭南地区汉族人群17个Y-STR基因座多态性及遗传关系分析[J]. 人类学学报, 2014, 33(02): 230-236.
[15]	张兴华; 郑连斌; 宇克莉; 包金萍; 王志博; 武亚文; 宋瓘兰. 山东寿光汉族体质特征[J]. 人类学学报, 2011, 30(02): 206-217.